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John G Gribben Selected Research

Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)

1/2015High Throughput Sequencing Analysis of the Immunoglobulin Heavy Chain Gene from Flow-Sorted B Cell Sub-Populations Define the Dynamics of Follicular Lymphoma Clonal Evolution.
7/2014Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia.
7/2011A unique proteomic profile on surface IgM ligation in unmutated chronic lymphocytic leukemia.
4/2011Chemoimmunotherapy with fludarabine and rituximab produces extended overall survival and progression-free survival in chronic lymphocytic leukemia: long-term follow-up of CALGB study 9712.
9/2008Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia.
3/2008Nonstochastic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3.
10/2005Distinctive IGH gene segment usage and minimal residual disease detection in infant acute lymphoblastic leukaemias.
8/2004ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia.
7/2002Real-time polymerase chain reaction estimation of bone marrow tumor burden using clonal immunoglobulin heavy chain gene and bcl-1/JH rearrangements in mantle cell lymphoma.

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John G Gribben Research Topics

Disease

61B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2022 - 07/2002
50Neoplasms (Cancer)
01/2022 - 01/2002
26Lymphoma (Lymphomas)
01/2022 - 03/2002
18Leukemia
01/2022 - 10/2004
17Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
01/2022 - 11/2006
10Disease Progression
01/2022 - 08/2004
10Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2018 - 01/2002
9Residual Neoplasm
01/2022 - 12/2003
8Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2022 - 01/2002
8Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2022 - 01/2012
7Graft vs Host Disease (Graft-Versus-Host Disease)
01/2021 - 05/2006
5Hodgkin Disease (Hodgkin's Disease)
01/2019 - 04/2012
5B-Cell Lymphoma (Lymphoma, B Cell)
10/2016 - 07/2013
4Hematologic Neoplasms (Hematological Malignancy)
10/2016 - 03/2005
4Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
06/2015 - 12/2003
3Multiple Myeloma
01/2022 - 06/2002
3Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
01/2020 - 03/2002
2Neoplasm Metastasis (Metastasis)
10/2020 - 05/2005
2Infections
10/2019 - 11/2018
2Neutropenia
10/2019 - 11/2018
2Autoimmune Diseases (Autoimmune Disease)
01/2018 - 01/2016
2Acquired Immunodeficiency Syndrome (AIDS)
01/2015 - 07/2013
2Myelodysplastic Syndromes (Myelodysplastic Syndrome)
05/2006 - 01/2002
1Hypertension (High Blood Pressure)
01/2022
1Tertiary Lymphoid Structures
01/2021
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2021
1Breast Neoplasms (Breast Cancer)
10/2020
1Tumor Lysis Syndrome
01/2020
1Leukopenia
10/2019
1Sudden Death
01/2019
1Carcinogenesis
01/2019
1Neuroendocrine Carcinoma
01/2019
1Crohn Disease (Crohn's Disease)
01/2018
1Virus Diseases (Viral Diseases)
01/2018
1T-Cell Leukemia (Leukemia, T Cell)
01/2018

Drug/Important Bio-Agent (IBA)

15Rituximab (Mabthera)FDA Link
02/2021 - 03/2002
10AntigensIBA
01/2017 - 09/2002
10Immunoglobulins (Immunoglobulin)IBA
04/2009 - 03/2002
9obinutuzumabIBA
01/2022 - 08/2016
9Lenalidomide (CC 5013)FDA Link
10/2019 - 09/2009
9fludarabineIBA
11/2018 - 02/2004
9Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
01/2015 - 07/2002
8Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2018 - 03/2002
7ibrutinibIBA
01/2022 - 01/2018
7Biomarkers (Surrogate Marker)IBA
10/2020 - 03/2008
6Chlorambucil (Leukeran)FDA Link
01/2022 - 04/2014
5LigandsIBA
10/2016 - 08/2012
4Pharmaceutical PreparationsIBA
01/2022 - 07/2008
4Phosphotransferases (Kinase)IBA
01/2022 - 02/2014
4Doxorubicin (Adriamycin)FDA LinkGeneric
09/2015 - 03/2002
4Monoclonal AntibodiesIBA
03/2009 - 01/2002
3venetoclaxIBA
01/2020 - 01/2019
3HMGB1 Protein (HMG1)IBA
01/2019 - 03/2014
3Bendamustine HydrochlorideFDA Link
01/2018 - 08/2016
3DNA (Deoxyribonucleic Acid)IBA
11/2017 - 06/2005
3Isoantigens (Alloantigen)IBA
01/2016 - 09/2008
3Vincristine (Oncovin)FDA LinkGeneric
09/2015 - 03/2002
3Prednisone (Sone)FDA LinkGeneric
09/2015 - 03/2002
3Proteins (Proteins, Gene)FDA Link
06/2014 - 01/2003
3AntibodiesIBA
05/2013 - 08/2008
3Alemtuzumab (Campath)FDA Link
01/2011 - 07/2006
2Chimeric Antigen ReceptorsIBA
01/2022 - 12/2013
2EnzymesIBA
01/2022 - 06/2015
2Immunoglobulin Variable RegionIBA
12/2020 - 03/2007
2AnthracyclinesIBA
10/2020 - 04/2012
2CytokinesIBA
01/2018 - 01/2003
2Biological ProductsIBA
01/2013 - 07/2008
2Bortezomib (Velcade)FDA Link
01/2012 - 11/2008
2Actins (F Actin)IBA
09/2010 - 11/2009
1axicabtagene ciloleucelIBA
01/2022
1Serine (L-Serine)FDA Link
01/2022
1Lysine (L-Lysine)FDA Link
01/2022
1Agammaglobulinaemia Tyrosine KinaseIBA
10/2021
1GemcitabineFDA Link
01/2021
1ChemokinesIBA
01/2021
1Estrogen ReceptorsIBA
10/2020
1Phenobarbital (Luminal)FDA Link
10/2020
1Focal Adhesion Protein-Tyrosine KinasesIBA
10/2020
1TamoxifenFDA LinkGeneric
10/2020
1Progesterone Receptors (Progesterone Receptor)IBA
10/2020
1CateninsIBA
01/2020
1NF-kappa B (NF-kB)IBA
01/2020
1ethyl pyruvateIBA
01/2019
1serum P-component (CIt)IBA
11/2018
1ofatumumabFDA Link
11/2018
1Therapeutic UsesIBA
01/2018
1FlavonoidsIBA
01/2018
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2018
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
01/2018
1wogoninIBA
01/2018

Therapy/Procedure

41Therapeutics
01/2022 - 01/2002
20Stem Cell Transplantation
01/2018 - 01/2002
15Drug Therapy (Chemotherapy)
01/2021 - 01/2002
11Immunotherapy
01/2021 - 06/2002
10Hematopoietic Stem Cell Transplantation
01/2021 - 07/2003
8Transplantation
01/2018 - 01/2002
6Bone Marrow Transplantation (Transplantation, Bone Marrow)
09/2008 - 01/2003
3Highly Active Antiretroviral Therapy (HAART)
01/2015 - 11/2012
1Neoadjuvant Therapy
10/2020
1Adjuvant Radiotherapy
10/2020